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The World Health Organization

Selected publications and documents on Diarrhoeal Diseases (including cholera) from the World Health Organization
 

 


This page represents a list of selected WHO online publications and documents relating to the Control and Management of Diarrhoeal Diseases and Cholera. It is not a complete list. 

These can be viewed in electronic format online, or downloaded for offline viewing.  Use your browsers Find / Search function to assist you in locating a subject, country or keyword 
 

 
 
 

WHO directory Contact information for regional and field offices. 
WHO European Regional Office  


Major Publications 


World Health Report 
The World Health Report 2000 Health Systems: Improving Performance is an expert analysis of the increasingly important influence of health systems in the daily lives of people worldwide.

Previous World Health Reports
 
Fifty facts from the World Health Report 1998  
Global health situation and trends 1955-2025 - Population: 1. The global population was 2.8 billion in 1955 and is 5.8 billion now. It will increase by nearly 80 million people a year to reach about 8 billion by the year 2025. 
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WHO Report on Infectious Diseases 
Illness and death from infectious diseases can be, in most cases, avoided at an affordable cost. Those who have received this report have a unique responsibility, as they are leaders in society who can make a substantial contribution to the prevention and control of infectious diseases. 
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url: http://www.who.int/infectious-disease-report/index-rpt99.html 

Health and Environment in Sustainable Development: 
This is an executive summary of the WHO report Health and Environment in Sustainable Development: Five Years after the Earth Summit. The summary contains extracts from the report, selected figures and tables, and the conclusions in full. To promote ease of reference, section headings and numbers of figures and tables have been maintained as used in the report. Bibliographic references have been excluded, however.

The report is a contribution by WHO to the five-year follow-up to the Earth Summit. This anniversary has provided an opportunity to assess the impact made by environmental health activities at local, national and global level during this period. The book brings together systematically quantitative data on health-and-environment linkages at the global level, with examples from regions and countries. Such linkages have already been described in the 1972 WHO report Health hazards of the human environment and in the 1992 WHO report Our planet, our health, but new information and new ways of considering health and environment issues have since emerged and form the basis of this report.
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url: http://www.who.int/environmental_information/Information_resources/htmdocs/execsum.htm 

Dr. Gro Harlem Brundtland, Director-General, World Health Organization - Speeches 
          Health for the 21st Century 
          Breaking the Poverty Cycle: Investing in Early Childhood 
          Weather, Climate and Health 
          Science and Health: WHO's Perspective 
          Epidemic of Tuberculosis – A Global Threat  
          How far have we come and where should we be going? 
          Global Trends in Child Health 

Other WHO reports

Documentation Centres

World Health Assembly Documentation
Documentation related to the World Health Assembly. Available in multiple languages.

About WHO 

The World Health Organization
Headquarters Office in Geneva (HQ)

Avenue Appia 20
1211 Geneva 27
Switzerland 

Telephone: (+00 41 22) 791 21 11
Facsimile (fax): (+00 41 22) 791 3111
Telex: 415 416
Telegraph: UNISANTE GENEVA 

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  • If you would like to request general information about WHO or current WHO events or if you need information for newspaper, TV, radio or other media reports, please email info@who.int
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Regional and Other Offices

 About WHO: Diarrhoeal Diseases 

About WHO: Diarrhoeal Diseases 
Annually, at least 1 500 million episodes of diarrhoea occur in children under the age of five. An estimated 4 million children die each year as a result. Diarrhoea removes essential body fluids and vital nutrients, producing dehydration and Malnutrition.
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url: http://www.who.int/aboutwho/en/preventing/diarrhoeal.htm 

About WHO : Integrated Management of Childhood Illness
Every year some 12 million children die before they reach their fifth birthday, many of them during the first year of life. Seven in every ten of these child deaths are due to diarrhoea, pneumonia, measles, malaria or malnutrition -  and often to a combination of these conditions. At least three out of four children taken to health facilities for care are suffering from one of these five conditions. 
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url: http://www.who.int/aboutwho/en/preventing/integratedm.htm 

About WHO: Preventing and Controlling Specific Health Problems 
Vaccine-preventable diseases, Tropical diseases,  Malaria, Tuberculosis, Diarrhoeal diseases, Acute respiratory infections, Integrated management of childhood illness, HIV/AIDS, Sexually transmitted diseases, New and emerging infectious diseases, heart disease, mental health 
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url: http://www.who.int/aboutwho/en/preventing/preventing.htm 

About WHO: Food Safety 
Food safety Hundreds of millions of people suffer from communicable diseases caused by contaminated food (including drinking water), which can be a major vehicle for cholera and other forms of epidemic diarrhoeal diseases, resulting in some 3 million deaths each year. Up to 70% of diarrhoea episodes in infants may be food borne in origin. 
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url: http://www.who.int/aboutwho/en/promoting/food.htm 

About WHO: Monitoring the Environment 
Access to safe drinking-water is essential for health and well-being. Since the end of the International Drinking Water Supply and Sanitation Decade (1981-1990), progress and investments in reaching the rural and periurban poor have been lagging. Over 1 000 million people do not have even minimal facilities for sanitary excreta disposal. More than 2.5 million infants and young children die each year from diarrhoeal diseases related to unsafe and poor sanitation, while approximately 1 500 million people are infected by intestinal worms resulting from faecal-oral contamination. 
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url: http://www.who.int/aboutwho/en/promoting/monitor.htm 

Integrated Management of Childhood Illness (IMCI) 

Integrated Management of the Sick Child 
While a great deal has been learned from disease-specific control programmes during the past 15 years, the challenge remained of how to combine the lessons learned into a single method for more efficient and effective management of childhood illness. WHO and UNICEF responded by jointly developing an approach referred to as integrated management of the sick child.
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url: http://www.who.int/inf-fs/en/fact096.html 

Reducing mortality from major killers of children  
Each year, more than eleven million children die from the effects of disease and inadequate nutrition. In some countries, more than one in five children die before they reach their fifth birthday, and many of those who do survive are unable to grow and develop to their full potential.

Seven out of 10 of childhood deaths in developing countries can be attributed to just five main causes, or often to a combination of them: pneumonia, diarrhoea, measles, malaria and malnutrition. Around the world, three out of every four children seen by health services are suffering from at least one of these conditions. 
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url: http://www.who.int/inf-fs/en/fact178.html 

Child Health Division 

WHO Child Health and Development  
Integrated Management of Childhood Illness, Acute Respiratory Infections, Diarrhoeal Diseases Cholera Documents, FAQ's, Links, Search, CHD IntraNet 
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url: http://www.who.int/chd/ 

Links to Child Health Resources  
Division of Child Health and Development (CHD) World Health Organization 
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url: http://www.who.int/chd/links/linkmenu.htm 

Division of Diarrhoeal and Acute Respiratory Disease Control 
Diarrhoea and acute respiratory infections each kill more children under 5 than any other disease. The World Health Organization (WHO) estimates that in 1990 diarrhoea caused 3.2 million deaths in this age group and acute respiratory infections (ARI) a further 4.3 million deaths. 

These 7.5 million deaths accounted for over half of all deaths among children under 5. Some of the ARI-related deaths were due to the respiratory manifestations of two diseases preventable by immunization: measles and whooping cough, but the vast majority were due to pneumonia. Half of the diarrhoea deaths were due to dehydration. Almost all of the deaths could have been prevented with simple, cheap treatment. 

Each year children under 5 throughout the world suffer over 1.3 billion episodes of diarrhoea and 40 million episodes of pneumonia. For those who survive, these illnesses are major factors in their poor nutritional state. 
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url: http://www.who.int/chd/publications/cdd/pofact77.htm 

CHD programme report 1996  
This interim report covers 1996, the first year of the current biennium. A more complete report of the Division's activities will be prepared at the end of the biennium. The report describes the activities of the WHO Headquarters' Division of Child Health and Development (CHD) and of its counterparts in the WHO regional offices and in countries. 
     Introduction 
  I. Technical Support to Countries 
  II. Health Systems Practices and Programme Managemant Methods 
III. Family and Community Practices
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url: http://www.who.int/chd/report/intro.htm 

Oral Rehydration 

Rice-based ORS 
Oral rehydration therapy (ORT) using the WHO/UNICEF glucose-based Oral Rehydration Salts (ORS) solution is the preferred method for treating most children with dehydration due to diarrhoea (except those with severe dehydration); it has been used successfully in millions of cases worldwide. In many countries glucose-ORS solution is also recommended for home treatment of children with diarrhoea after they have been seen at a health facility, even when there are no signs of dehydration. Glucose-ORS solution works because glucose is rapidly absorbed by most patients with diarrhoea, and this causes salt and water also to be absorbed, thus replacing the faecal losses. 

Although glucose-ORS solution efficiently replaces faecal losses of water and salts, it has one important shortcoming: it does not reduce stool volume during diarrhoea or shorten the duration of the illness, which are the results that mothers and many health workers seek. If an ORS formulation could be developed that had the positive features of the standard glucose-ORS, including low cost safety, and stability during prolonged storage, but also appreciably reduced the rate of stool loss during illness and/or the duration of diarrhoea, it could have considerable advantages over glucose-ORS. Most importantly, it could be promoted as having a true antidiarrhoeal effect, which should lead to increased acceptance and use of ORS by both health workers and mothers, and perhaps also to a reduction in the use of ineffective "antidiarrhoeal" drugs and inappropriate antibiotics. This would represent a major advance in efforts to control diarrhoeal morbidity and mortality through appropriate case management. 

Clinical trials of rice-based ORS: Recent studies suggest that an ORS with these advantages may be possible. The first evidence came from clinical trials in Bangladesh and India, which showed that dehydrated diarrhoea patients given an ORS solution containing 50 grams of cooked rice powder in place of the usual 20 grams of glucose were satisfactorily rehydrated and had an appreciably reduced rate of stool output during treatment as compared with patients given glucose-ORS solution. 
No. 7, August 1990 
url: http://www.who.int/chd/publications/newslet/update/updt-07.htm 

Education and Training - Manuals and Guidelines 

Diarrhoea Management Training Course 
- Introduction
 
Guidelines for Conducting Clinical Training Courses at Health Centres and Small Hospitals
Diarrhoeal diseases are a leading cause of childhood mortality and morbidity in the developing world. These deaths are caused by dehydration, dysentery, and persistent diarrhoea. Dehydration from acute diarrhoea of all etiologies and in all age groups can be treated safely and effectively by the simple method of oral rehydration therapy (ORT). 
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url: http://www.who.int/chd/publications/cdd/dmtc/dmtcintr.htm 

Diarrhoea Management Training Course 
- Chapter 1: Training Objectives
 
Exactly what the training includes, how it is done, and how long it takes will differ from one facility to another. These things will depend on the number and type of participants and the resources and capabilities 
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url: http://www.who.int/chd/publications/cdd/dmtc/dmtc1.htm 

Diarrhoea Management Training Course 
- Chapter 2: Handling Administrative Arrangements
 
Careful administrative planning is essential for the training to be successful. The planning steps are listed below. One or two instructors may do all of these steps, but it is advisable that the team of instructors and staff participate. Suggestions for each of these steps are provided in greater detail in this chapter. 
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url: http://www.who.int/chd/publications/cdd/dmtc/dmtc2.htm 

Clinical Skills: A Self-Instructional Course 
The Clinical Skills training course is designed to teach health workers to assess and treat cases of diarrhoea properly and to educate families about prevention and home treatment of diarrhoea. Primarily self-instructional, Clinical Skills is the first course designed especially for health workers who may be unable to attend a training course away from their worksites, but who have the important responsibility of treating diarrhoea. 
url: http://www.who.int/chd/publications/newslet/update/updt-19.htm 

Medical Education: Teaching Medical Students about Diarrhoeal Diseases 
Strengthening the Teaching of Diarrhoeal Diseases in Medical Schools - "Readings on Diarrhoea" is intended for medical students, especially during their clinical training in pediatrics. It will also be useful for physicians participating in training courses on the management of diarrhoea in children. The materials in this book are compatible with other WHO publications on the management and prevention of diarrhoea. Units that concern the management of children with diarrhoea are based on the WHO treatment chart "Management of the Patient with Diarrhoea" (1990). Portions of that chart are reproduced at appropriate places in this text.

There are eight units to the training program:

The epidemiology and etiology of diarrhoea 
Pathophysiology of diarrhoea 
Assessing the diarrhoea patient 
Treatment of diarrhoea at home 
Treatment of dehydrated patients 
Dysentery, persistent diarrhoea and diarrhoea associated with other diseases 
Diarrhoea and Nutrition 
Prevention of Diarrhoea 

url: http://www.who.int/child-adolescent-health/New_Publications/CHILD_HEALTH/Meded  

Topics in International Health 
Produced by the Wellcome Trust for use as an educational resource in tropical and international health. The series is divided into numerous CDs, each focusing on a specific disease or group of diseases. 
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url: http://www.who.int/hlt/otherdata/English/topics.htm 

Strengthening the Teaching of Diarrhoeal Diseases in Basic Training Programmes
Manual for Instructors of Nurses and Other Health Workers
 
Advising Mothers on Management of Diarrhoea in the Home:
Instructions for Facilitators.
 
This guide teaches a process and skills which will help the health worker to advise mothers on home case management correctly and effectively. The process will help the health worker to communicate all the essential information to the mother in a structured manner, and in a reasonable amount of time. It will also help the health worker to limit the amount of information to give, and it should make it easier for mothers to remember the advice. 
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url: http://www.who.int/chd/publications/cdd/advising/adv_mom2.htm 

Diarrhoea Case Management 

The Treatment of Diarrhoea: A Manual for Physicians and Other Senior Health Workers 
Diarrhoeal diseases are a leading cause of childhood morbidity and mortality in developing countries, and an important cause of malnutrition. On average, children below 3 years of age in developing countries experience three episodes of diarrhoea each year. In 1993 an estimated 3.2 million children below 5 years died from diarrhoea. Eight out of 10 of these deaths occur in the first two years of life. In many countries diarrhoea, including cholera, is also an important cause of morbidity among older children and adults. 

  1. Introduction, 
  2. Essential concepts concerning diarrhoea, 
  3. Assessment of the child with diarrhoea, 
  4. Management of acute diarrhoea without blood, 
  5. Management of suspected cholera, 
  6. Management of acute bloody diarrhoea (dysentery), 
  7. Management of persistent diarrhoea, 
  8. Management of diarrhoea with severe malnutrition, 
  9. Other problems associated with diarrhoea, 
  10. Antimicrobials and drugs, 
  11. Prevention of diarrhoea, 

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url: http://www.who.int/chd/publications/cdd/textrev4.htm 

How Research Findings Have Improved Diarrhoea Case Management 
1. Practical application of research,  2. Treatment advice for diarrhoea -  WHO's Division of Diarrhoeal and Acute Respiratory Disease Control (CDR), among its many activities, supports research into ways of preventing and treating diarrhoeal diseases. The research is coordinated by CDR's Programme for Diarrhoeal Disease Control (CDD). Over the years this research has evaluated a number of new or improved approaches to the control of diarrhoeal diseases. 
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url: http://www.who.int/chd/publications/newslet/update/updt-20.htm 

Improving the Practices of Pharmacists and Licensed Drug Sellers  
1. Pharmacists as health care workers, 2. Successful training methods, 3. What field tests show - The importance of the private sector - If diarrhoea in children is to be managed correctly, there is need to look beyond public sector health facilities. Good management has to be promoted in the home, and there is also a need to improve the practices of all providers of care, particularly in the private sector. 
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url: http://www.who.int/chd/publications/newslet/update/updt-18.htm 

Treatment of Diarrhoeal Diseases: Information for Pharmacists and other Drug Sellers 
This guide contains information aimed at improving the practices of drug sellers in the treatment of diarrhoea. It is divided into nine sections: 

  1. 1.How to use this guide
  2. 2.Choosing a target audience
  3. 3.Analyzing the target audience
  4. 4.Factors influencing drug sellers' practices
  5. 5.Planning an intervention
  6. 6.Developing printed materials
  7. 7.Training staff and testing the intervention
  8. 8.Monitoring and evaluation
  9. 9.Carrying out the intervention 

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url: http://www.who.int/chd/publications/cdd/pharm/intro.htm 

The Outpatient Management of Bloody Diarrhoea in Young Children 
1. What causes bloody diarrhoea, 2. Practical guidelines for treatment -  About 10% of diarrhoeal episodes in children under 5 years of age have visible blood in the stool and these cause about 15% of diarrhoea-associated deaths in this age group. Compared with watery diarrhoea, bloody diarrhoea generally lasts longer, is associated with more complications, is more likely to adversely affect a child's growth, and has a higher risk of death. 
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url: http://www.who.int/chd/publications/newslet/update/updt-16.htm 

The Management of Bloody Diarrhoea in Young Children 
Bloody diarrhoea in young children is usually a sign of invasive enteric infection that carries a substantial risk of serious morbidity and death. This is especially true in the developing countries, where the problem occurs most frequently. Non-infectious causes account for a very small proportion of episodes of bloody diarrhoea. 
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url: http://www.who.int/chd/publications/cdd/bloody_d.htm 

Disease Outbreak 
 
1999 - Acute Diarrhoea in Sudan 
The outbreak of acute diarrhoea which began in early March is continuing. The areas of Padak, Mading, Wanding, Lankien, Akobo and Burmat have reported a total of 892 cases with 24 death up to 27 April 1999.
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url: http://www.who.int/emc/outbreak_news/n1999/apr/n30bapr1999.html 

1999 - Diarrhoeal Disease / Cholera in Congo 
WHO has been informed of an outbreak of diarrhoeal disease in Brazzaville, Congo. Some cholera cases have now been confirmed in this outbreak and more details on the current situation will be given as soon as they are available.
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url: http://www.who.int/emc/outbreak_news/n1999/mar/n17cmar1999.html 

1999 - Acute Watery Diarrhoea in Sudan 
As of 19 March, 78 deaths caused by acute watery diarrhoea had been reported. The total number of cases is unknown. Investigations are being carried out by the Ministry of Health. 
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url: http://www.who.int/emc/outbreak_news/n1999/mar/n26amar1999.html 

1998 - Bloody Diarrhoea in Cameroon 
Shigella dysenteriae type 1 (Sd1) has been confirmed as the organism responsible for the outbreak of bloody diarrhoea which started in Cameroon in November 1997. Since then 237 cases with 60 deaths have been reported. 
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url: http://www.who.int/emc/outbreak_news/n1998/apr/n29apr1998.html 

1998 - Cholera / Diarrhoea Outbreak in Liberia 
The national health authorities of Liberia have reported an outbreak of cholera/diarrhoea which started at the end of May. The areas affected by the outbreak are Nimba County and Margibi County. Up to 26 June a total of 560 cases with 12 deaths had occurred. 
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url: http://www.who.int/emc/outbreak_news/n1998/aug/n03aug1998.html 

1998 - Cholera / Acute Diarrhoea in Somalia 
A significant increase in the number of cases of acute diarrhoea has been reported to WHO by Médecins sans frontières (Spain), who have opened their cholera treatment centre in North Mogadishu as a result. An average of 14 cases are being admitted daily to this facility. 
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url: http://www.who.int/emc/outbreak_news/n1998/dec/n18dec1998.html 

1998 - Cholera-like Diarrhoeal Disease in the Congo 
Since November 1997, 445 cases of which 83 were fatal (case fatality rate 20%) have been reported in Pointe-Noire in the southern part of the country. The cases occurred between 7 November 1997 and 27 January 1998. 
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url: http://www.who.int/emc/outbreak_news/n1998/feb/n3feb1998a.html 

1998 - Diarrhoeal Diseases in Bangladesh 
The devastating floods which are sweeping the country began in early July this year and 52 districts out of a total of 64 with nearly 20 million people (25% of the total population) are affected. The death toll was reported as 730 up to 7 September 1998. Most of the districts currently affected are also endemic for diarrhoeal diseases and some outbreaks of acute diarrhoea have occurred. Over 185,OOO people have so far been affected and 151 have died. 
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url: http://www.who.int/emc/outbreak_news/n1998/sept/n30sept1998.html 

Bangladesh - Diarrhoeal Diseases in Bangladesh 
The devastating floods which are sweeping the country began in early July this year and 52 districts out of a total of 64 with nearly 20 million people (25% of the total population) are affected. The death toll was reported as 730 up to 7 September 1998. Most of the districts currently affected are also endemic for diarrhoeal diseases and some outbreaks of acute diarrhoea have occurred. Over 185,000 people have so far been affected and 151 have died. 
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url: http://www.who.int/eha/emergenc/bangla/021098.htm 

Cases of Acute Bloody Diarrhoea in a Rural District by Month 
January 1994- April 1995 Objective: To detect outbreaks of dysentery by monitoring the incidence of cases of acute bloody diarrhoea. Slide 7 of 32 ...
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url: http://www.who.int/csr/labepidemiology/surveillancesystems/en/ 

Epidemic Control 

Mozambique - The Fight Against Disease Increases 
The next two to eight weeks are critical for Mozambique's health and aid workers fighting the threat of potential cholera and malaria epidemics, said the World Health Organization (WHO) today. The threat of a malaria epidemic in the country is increasing and will be at its most dangerous in around three to six weeks time as floodwaters gradually subside, the rains stop and warm temperatures return – ideal breeding conditions for mosquitoes.
url: http://www.who.int/inf-pr-2000/en/pr2000-16.html 

Guidelines for Cholera Control 
These guidelines have been prepared by the Global Task Force on Cholera Control of the World Health Organization to help managers of national programmes for control of diarrhoeal diseases and others responsible for implementing cholera control activities. They may also be useful to international, bilateral, and nongovernmental agencies when deciding on appropriate assistance to countries for controlling cholera outbreaks. 
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url: http://www.who.int/chd/publications/cholera/cholguid.htm 

Epidemic Diarrhoeal Disease Preparedness and Response. Training and Practice.
Participant's Manual
 
Introduction, Chapter 1: Preparedness and Detection, Chapter 2: Response, Chapter 3: Control Measures, Exercise Y: Case study (Rivas District outbreak) 
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url: http://www.who.int/emc-documents/cholera/whoemcdis973c.html 

Epidemic Diarrhoeal Disease Preparedness and Response. Training and Practice.
Facilitator's Guide
 
Introduction, Checklist of Instructional Materials Needed at the Course, Checklist of Supplies Needed at the Course, Materials and Information to be Obtained before the Course Begins, Space Requirements Guidelines on Techniques, Detailed Guidelines, Summary of Chapter 1, Summary of Chapter 2, Summary of Chapter 3, Annexes, Annex 1: Evaluation, Annex 2: Sample draft for invitation letter, Annex 3: Suggested timetable 
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url: http://www.who.int/emc-documents/cholera/whoemcdis974c.html 

Review of the Project for Improving Preparedness and Response to Cholera and Other Epidemic Diarrhoeal Diseases in Southern Africa 
In 1993 following the concern of Southern African countries over the yearly epidemics of cholera that have been occurring since the late 1980's and the spread of epidemic dysentery in the region, a sub-regional programme was initiated by WHO to help countries affected to improve their capacity to be prepared and respond to epidemic diarrhoeal diseases. The programme was funded by voluntary contributions from Switzerland, Australia, Italy and the United States. The sub-regional team worked with Ministries of Health and other involved national government sectors, international agencies, as well as with non-governmental organizations. After three years project implementation, a joint evaluation team composed of WHO Headquarters and Regional Office for Africa, plus donors, met in Harare to review the outcome of the project. The evaluation group concluded that the project was very successful and should be replicated in other regions. 

Executive Summary, Background/Project Description, Purpose and Methods of the Review, Overall Achievements of the Project, Laboratory Strengthening, Analysis of the Status of the Project Implementation, Lessons Learned, Critical Activities to be Continued and Recommended Duration of Support, Replicability of Project, Recommendations
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url: http://www.who.int/emc-documents/cholera/whoemcdis975c.html 
url: http://www.who.int/emc-documents/cholera/docs/whoemcdis975.html 

Cholera and Other Epidemic Diarrhoeal Diseases Control.
Technical Cards on Environmental Sanitation
 
Planning and management topics
 - Emergency Interventions for Cholera Outbreaks 
 - Estimating Requirements for Water Quality Monitoring and Control 
 - Community Planning for Diarrhoeal Disease Control 
Technology selection and construction topics
 - Well Sinking in Non-Collapsing Formations 
 - Spring Protection 
 - Excreta Disposal Options 
 - Septic Tank Systems for Peri Urban Areas 
 - Ventilated Improved Pit Latrines 
 - Rainwater Harvesting Systems 
Technology maintenance
 - Afridev Handpump Maintenance 
 - Repair of the Model "A" Bushpump 
Water quality and hygiene topics
 - Household Water Treatment and Storage 
 - Disinfectants 
 - Cleaning and Disinfection of Wells 
 - Dosing Water with Hypochlorite Solutions 
 - Testing for Chlorine 
 - Cleaning and Disinfection of Storage Tanks, Tanker Trucks and Pipelines 
 - Sanitary Surveillance of Wells and Boreholes 
 - Sanitary Surveillance of a Distribution System 
 - Collection of Water Samples – Sampling 
 - Collecting Water Samples - Methods 
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url: http://www.who.int/emc-documents/cholera/whoemcdis976c.html 

Guidelines for the Control of Epidemics Due to Shigella Dysenteriae Type 1 
Shigella dysenteriae type 1 (Sd1) is an unusually virulent enteric pathogen that causes endemic or epidemic dysentery with high death rates. It is the only cause of large-scale, regional outbreaks of dysentery. In recent years, Sd1 has caused epidemic dysentery in Central America, south Asia, and central and southern Africa. An epidemic in Central America from 1969 to 1973 was responsible for more than 500,000 cases and 20,000 deaths. The epidemic in central and southern Africa began in 1979 and has affected at least nine countries. It is likely that most developing countries are at risk of epidemic dysentery due to Sd1. 

These guidelines are intended to assist national health authorities, public health officers and health care providers in their efforts to prevent and/or treat Sd1 disease. The text describes the epidemiology, clinical features and management of disease caused by Sd1, and interventions that can reduce both the incidence of Sd1 infections and mortality due to Sd1 disease.  
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url: http://www.who.int/chd/publications/cholera/shig4g.htm 
url: http://www.who.int/emc-documents/cholera/whocdr954c.html 

Cholera 

Cholera - WHO Fact Sheet 
Surveillance and Response Global incidence, epidemiology, disease outbreaks, articles and publications, videos WHO Publications Diarrhoeal Diseases Infectious, Emerging Diseases International Travel and Health vaccination requirements and health advice
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url: http://www.who.int/health-topics/cholera.htm 

Cholera - WHO Fact Sheet
Cholera is an acute intestinal infection caused by the bacterium Vibrio cholerae. It has a short incubation period, from less than one day to five days, and produces an enterotoxin that causes a copious, painless, watery diarrhoea that can quickly lead to severe dehydration and death if treatment is not promptly given. Vomiting also occurs in most patients.
Fact Sheet N107- Revised March 2000 
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url: http://www.who.int/inf-fs/en/fact107.html 

Some Frequently Asked Questions About Cholera 
What is cholera? How is cholera spread? Where do outbreaks occur? Can cholera be prevented? What treatments are available? What about antibiotics and other drugs? Do vaccines confer protection?
url: http://www.who.int/emc/diseases/cholera/questionsaboutcholera.html 

Management of the Patient with Cholera 
Cholera should be suspected when: - a patient older than 5 years develops severe dehydration from acute watery diarrhoea (usually with vomiting); or - any patient above the age of 2 years has acute watery diarrhoea in an area where there is an outbreak of cholera. 

Steps in the management of suspected cholera: Step 1. Assess for dehydration, Step 2. Rehydrate the patient, and monitor frequently. Then reassess hydration status, Step 3. Maintain hydration: replace ongoing fluid losses until diarrhoea stops, Step 4. Give an oral antibiotic to the patient with severe dehydration, Step 5. Feed the patient.
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url: http://www.who.int/emc-documents/cholera/docs/whocddser9115.html 
url: http://www.who.int/chd/publications/cholera/cholman.htm 
url: http://www.who.int/emc-documents/cholera/whocddser9115c.html 

WHO Guidance on Formulation of National Policy on the Control of Cholera 
Adequate surveillance and reporting is essential for national and international efforts to control cholera. Case definitions: The primary purpose of collecting and reporting information on cases of cholera is to facilitate local and national control efforts. As cholera is notifiable under the terms of the International Health Regulations, standard definitions should be used and certain information should be included in reports from all levels of the health system.

  1. Surveillance and reporting 
  2. The use of the laboratory 
  3. Cholera Immunization 
  4. Control of International spread of cholera 
  5. Use of antibiotics 
  6. Tourism in cholera-affected areas 
  7. Water supply and sanitation 
  8. Cholera and food: General considerations 
  9. Cholera and International trade in food 
  10. Health Education 

url: http://www.who.int/chd/publications/cholera/cholpol.htm 

Cholera: Dealing with an Emergency 
Reporting, 1. Laboratory testing of stool specimens, 2. Common sources of infection, 3. Effective control measures, 4. Ineffective control measures, 5. Cholera treatment 
url: http://www.who.int/chd/publications/cholera/cholemer.htm 

Cholera - WHO Report on Global Surveillance of Epidemic-prone Infectious Diseases 
Chapter 4 - 1. Background of disease, 2. Description of the data, 3. Trends, 4. Conclusions, 5. References & links, 6. Tables 
url: http://www.who.int/emc-documents/surveillance/docs/whocdscsrisr2001.html/cholera/cholera.htm 

Cholera and Epidemic Dysentery 
Pointers to information about cholera and epidemic dysentery - Fact Sheets, WHO Report on Global Surveillance of Epidemic-prone Infectious Diseases - Cholera,  Global Data, Cholera in the Disease Outbreak News, Documents and Publications, Videos 
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url: http://www.who.int/emc/diseases/cholera/ 

Dysentery 

Dysentery - WHO Fact Sheet 
Epidemic Dysentery, Children: Reducing Mortality, Integrated Management of Childhood Diseases, Publications and documents on diarrhoeal diseases, Surveillance and Response, Epidemic dysentery: global incidence, epidemiology, disease outbreaks, articles and publications
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url: http://www.who.int/health-topics/diarrhoeal.htm 

Epidemic Dysentery 
Dysentery may be simply defined as diarrhoea containing blood. Although several organisms can cause dysentery, Shigella are the most important. Shigella dysenteriae type 1 (Sd1), also known as the Shiga bacillus, is the most virulent of the four serogroups of Shigella. Sd1 is the only cause of epidemic dysentery. 
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url: http://www.who.int/inf-fs/en/fact108.html 

Communication

Radio Guide: A Guide to Using Radio Spots in National CDD Programmes 
The keys to effective promotion via radio are creativity and repetition. Although there are various types of radio materials that could be used to support CDD programmes, both of these criteria are best fulfilled by using radio spots. For these reasons, the CDD Programme and the HealthCom Project, Academy for Educational Development, have developed a manual called Radio guide: A guide to using radio spots in national CDD programmes. 

This manual will interest national CDD programmes which actively promote home case management, which have some evidence that radio is an important channel in their country, and which are willing to commit the necessary time and resources. 
url: http://www.who.int/chd/publications/newslet/update/updt-15.htm 

Using Radio Spots to Support National CDD Programmes 
The main focus of national diarrhoeal disease control (CDD) activities is to assure the correct treatment of child diarrhoea. This involves teaching parents how to take care of their children during and after diarrhoea episodes, including when to seek help from health professionals. 

Face-to-face communication, such as that between a health worker and a caretaker, is the most effective way to teach parents how to treat their children during diarrhoea episodes. The WHO/CDD document Advising mothers on management of diarrhoea in the home teaches health workers the basic skills they need to advise parents how to manage their child's diarrhoea. But the advice given by health workers reaches only those people who come to health facilities, which may be only certain groups: families who live near enough to walk to the facility, or who can afford transport, or who are already convinced that the clinic is the best place to go for help, or those whose child is dangerously ill. In addition, a mother probably comes to the health facility only rarely, and it may be difficult for her to remember all the information learned at each visit. 

Radio can complement face-to-face communication in national CDD programmes because it: 
 - Reinforces the advice that health workers are giving,  
 - Reaches those people who do not come to health facilities. 
It can also: 
 - Help the CDD programme to promote behaviours that will help prevent diarrhoea
 - Help inform people and raise awareness about a new idea, a new product, or a service that is available. ("When your child has diarrhoea, help him to eat and drink so he will stay strong." "ORS (oral rehydration salts) packets are now available free at district health posts.") 
 - Create a demand for services. ("Ask the doctor for advice on how to encourage your child to eat during diarrhoea." "Ask the nurse how to mix ORS correctly.") 
 - Remind people what they have already learned. ("Remember to take your child to the clinic if her diarrhoea has blood in it.") 
 - Motivate people, by presenting information in a compelling or entertaining way. 
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url: http://www.who.int/chd/publications/cdd/radio.htm 

Vaccine and Immunization 

Diseases and Vaccines information - GPV, Global Programme for Vaccines and Immunization 
Vaccine research information from GPV, Global Programme for Vaccines and Immunization ...
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url: http://www.who.int/vaccines-research/ 

Vaccine Research and Development - Diarrhoeal Diseases
Cholera, Rotavirus, Shigella, Enterotoxic Escherichia Coli,Thyphoid Fever
 
Vaccine and Immunization information from GPV, Global Programme for Vaccines and Immunization - Overall Objective: to obtain effective and safe vaccines against enteric diseases which: are easy to deliver, can be delivered in one (or few) doses, can be incorporated into existing schedules of vaccine delivery and are robust enough to retain their protective properties in the adverse conditions likely to be encountered in the developing world.

The spectrum of pathogens covered includes bacterial organisms such as Vibrio cholerae, enterotoxic Escherichia coli (ETEC), Shigella dysenteriae and Shigella flexneri, and Salmonella typhi as well as rotaviruses. 
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url: http://www.who.int/vaccines-diseases/research/diarrhoea.shtml 

Rotavirus Vaccines 
Potential Rotavirus Vaccines: It has been estimated that an effective rotavirus vaccine could: reduce all diarrhoeal deaths by 30% in the age group 6-24 months, and avert 500,000 - 1,000,000 deaths in children annually. 
No. 5, March 1989 
url: http://www.who.int/chd/publications/newslet/update/updt-05.htm 

Shigella 
Vaccine and Immunization information from GPV, Global Programme for Vaccines and Immunization 
Four main species of Shigella, are able to cause diarrhoeal diseases: S. dysenteriae, S. flexneri, S. boydii, and S. sonnei. These species are divided in serotypes on the basis of the O-specific polysaccharide of the LPS. There are 12 serotypes of S. dysenteriae, 13 of S. flexneri, 18 of S. boydii and 1 of S. sonnei. S. flexneri is the predominant species in endemic areas, accounting for approximately 50% of culture-positive disease. S. flexneri is highly infectious by the oral route, and ingestion of as few as ten organisms can cause an infection in volunteers. Studies in animal models and epidemiological evidence in human populations indicate that Shigella infections elicit serotype-specific immunity. 
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url: http://www.who.int/vaccines-diseases/diseases/Shigella.shtml 

Surveillance and Response 

Disease Surveillance and Response 
The surveillance of a communicable disease is fundamental for disease prevention and control. Surveillance is defined as the "ongoing systematic collection, collation, analysis and interpretation of data; and the dissemination of information to those who need to know in order that action may be taken". 
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url: http://www.who.int/emc/surveill/index.html 

Principles of Surveillance - Slide show 
32 slides 
url: http://www.who.int/emc/slideshows/Survintro/sld001.htm 

EMC Document Centre - By Titles  
These documents offer an introduction to the activities and work of Communicable Disease Surveillance and Control. This department incorporates the former Division of Emerging and other Communicable Diseases Surveillance and Control and programmes from the Control of Tropical Diseases. 
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url: http://www.who.int/emc-documents/_titles.html 

EMC Document Centre - By Publication Year  
These documents offer an introduction to the activities and work of Communicable Disease Surveillance and Control. This department incorporates the former Division of Emerging and other Communicable Diseases Surveillance and Control and programmes from the Control of Tropical Diseases. 
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url: http://www.who.int/emc-documents/_year.html 

EMC Document Centre - By Subject  
These documents offer an introduction to the activities and work of Communicable Disease Surveillance and Control. This department incorporates the former Division of Emerging and other Communicable Diseases Surveillance and Control and programmes from the Control of Tropical Diseases. 
url: http://www.who.int/emc-documents/index.html 

WHO Recommended Surveillance Standards. Second Edition  
This document has been produced jointly by technical clusters of WHO, as well as by UNAIDS, in order to bring together WHO recommended standards for the surveillance of communicable diseases. It is not meant to replace existing technical guidelines or be an exhaustive description of surveillance of all diseases. This document serves only as a guide to good practice and may help to harmonize surveillance activities.

The purpose of this manual is to be a handy reference for key elements and contact information for all communicable diseases / syndromes associated with current WHO control programmes. It should be particularly useful at the Ministry of Health level in Member States, in approaching integrated surveillance of communicable diseases / syndromes. 
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url: http://www.who.int/emc-documents/surveillance/whocdscsrisr992c.html 

Breastfeeding 

Breast-Feeding and the Use of Water and Teas. 
Results from recent surveys indicate that the majority of neonates in Africa, Asia, and Latin America are breast-fed. However, the same surveys show that exclusive breast-feeding, i.e., giving the infant no other fluid or food than breast milk, is a very infrequent practice. Water and/or teas (such as camomile and fennel infusions) are offered to young infants, frequently from the first week of life, in the belief that they will relieve pain (e.g., from colic, earache), prevent and treat colds and constipation, soothe fretfulness, and, especially, quench thirst. 

The intake of such supplementary fluids is associated in young infants with an increased risk of disease and a shortening of the duration of breast-feeding. Moreover, several studies have shown that these fluids are not actually needed by healthy infants during the first semester of life if they are exclusively breast-fed. No. 1, Aug. 1992 
url: http://www.who.int/chd/publications/newslet/update/updt-09.htm 

Breastfeeding Counselling: A Training Course 
Breastfeeding: Training health workers. Health workers can play a key role in the protection, promotion and support of breastfeeding. Their presence at the time of delivery and their subsequent contacts with mothers and infants provide them with unique opportunities to help mother and baby to establish and maintain lactation. 

In the past two decades, there has been a rapid increase in our understanding, not only of the scientific basis of lactation and suckling, but also of effective management and prevention of breast-feeding problems, including the use of basic counselling skills. Research has shown that if health workers' attitudes and practices are supportive, it is more likely that mothers will breastfeed successfully and for a longer period. No. 14, Aug. 1994 
url: http://www.who.int/chd/publications/newslet/update/updt-14.htm 

Not Enough Milk and Breastfeeding 
WHO and UNICEF recommend that infants should be exclusively breastfed for at least the first four months of life, and if possible for 6 months. However, worldwide, few infants are breastfed exclusively for more than a few weeks. Even in societies where breastfeeding is still the norm, mothers often introduce complementary foods or drinks at an early age. One of the commonest reasons that mothers all over the world give for stopping breastfeeding or introducing complementary food early is that they think they do not have enough milk or that the quality of milk is poor. Some mothers worry about the amount of breastmilk they produce as early as the first days post-partum. No. 21 Feb. 1995 
url: http://www.who.int/chd/publications/newslet/update/updt-21.htm 

Hepatitis B and Breastfeeding 
The question of whether breastfeeding plays a significant role in the transmission of hepatitis B has been asked for many years. It is important given the critical role of breastfeeding and the fact that about 5% of mothers worldwide are chronic hepatitis B virus (HBV) carriers. Examination of relevant studies indicates that there is no evidence that breastfeeding poses any additional risk to infants of HBV carrier mothers. The use of hepatitis B vaccine in infant immunization programmes, recommended by WHO and now implemented in 80 countries, is a further development that will eventually eliminate risk of transmission. This document discusses the issues relevant to breastfeeding and HBV transmission, and provides guidance from a WHO perspective. No. 22 Nov 1996 
url: http://www.who.int/chd/publications/newslet/update/updt-22.htm 

Travel 

International Travel and Health 
This booklet is addressed to national health administrations responsible for providing advice on the health hazards of international travel, and to the practising physicians, travel agencies, shipping companies, airline operators, and other bodies who are called upon to give advice in individual cases. In addition to summarizing the vaccination requirements of individual countries, this booklet covers certain health hazards to which the traveller may be exposed and indicates the areas in which these hazards are most likely to occur. This is particularly important with malaria, which has continued to cause serious problems in recent years. It also recommends precautions that the wise traveller should take when visiting unfamiliar place

Cholera: Basic Facts for Travellers
What is cholera?, What should I do if I think I may have cholera?, Where are the outbreaks of cholera?, Do vaccinations work against cholera?, What can I do to avoid cholera? 
url: http://www.who.int/emc/diseases/cholera/factstravellers.html 

Cholera: Basic Facts for Travellers 
Cholera outbreaks occur every year in different parts of the world. Although potentially fatal, cholera can be easily prevented and treated. By following some simple and sensible rules, the traveller can avoid infection. Here are the basic facts about cholera. 
url: http://www.who.int/chd/publications/cholera/chobfact.htm 

WHO Publications: Travel Medicine  
A Guide on Safe Food for Travellers, International Certificates of Vaccination, International Health Regulations, International Medical Guide for Ships, International Travel and Health 2000 edition online, Ports Designated in Application of the International Health Regulations, Yellow Fever Vaccinating Centres for International Health 
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url: http://www.who.int/dsa/cat98/trav8.htm 

Reference 

WHO: List of Non-Governmental Organization Abbreviations 
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url: http://www.who.int/ina-ngo/ngo/z-abbrev.htm 

Anti-infective Drug Resistance  
WHO Global Strategy for Containment of Antimicrobial Resistance.  Despite the enormous advances in health care in the last half-century, infectious diseases still account for 25% of deaths worldwide and 45% in low-income countries. As we increasingly recognize the role of infectious agents